
Dive deep into this Lovecraft-inspired RTS survival. Assemble your team using different classes, skills, and weaponry. It's up to your squad to survive the onslaught of nightmares that are surely coming your way. Will you find the source of the darkness?
Modeled estimate, not a reported figure. How we estimate →
About

Real-time strategy gameplay mixed with Horror elements.

Squad based controls, multiple possibilities according to the way you build your team, soldiers are good killers, engineers can establish defense perimeter by building turrets, barricades or using special key points from the environment to build traps and medics can keep your team alive on a long run

During this stage, you choose which location you want to send your squad to search for supplies and information, you choose how you want to equip your survivors and what skills you want them to get stronger at, you choose your route and you decide the best course of action for the random events that will present before you.

This is not your classical zombie outbreak, no, this story is much darker inspired by Lovecraft works, an ancient evil has returned from below the earth bringing with him creatures of nightmare, abominations of unspeakable terror and if that was not enough, the dead humans are brought back to life as animated flesh to fight alongside this evil.

You are part of what remains of army forces, your brother, the one who took care of you when your parents died was also part of the army and went missing during a mission a few miles from where you are stationed with the objective to gather information about these underground holes from were these creatures are coming from. You decide to embark on one last journey of redemption to see your brother one more time.
Good luck Commander!
Genres
Stats
All-time low is the lowest price we've recorded for this game since we started tracking it.
Languages: English, Russian
Engagement
Hours played at review time, across 41 reviews with recorded playtime.
Reviews
Themes across 41 recent reviews and how positive each mention is. A keyword signal, not full sentiment analysis.
positive critical· bar length = how often the theme comes up
Reviews
Chromosome Evil is a dark, uncompromising blend of real-time squad tactics and survival horror that places tension and consequence at the center of its design. Developed and published by S.C. 16 BIT NIGHTS S.R.L., the game deliberately distances itself from conventional real-time strategy formulas, instead focusing on small-scale engagements, limited resources, and a suffocating atmosphere shaped by eldritch horror influences. From the very beginning, it communicates that survival is fragile and that every decision, from squad composition to movement across the map, carries weight. The setting is steeped in cosmic dread rather than straightforward apocalyptic collapse. An ancient, malevolent force has awakened, warping the land and transforming both the dead and the living into grotesque entities. This narrative framework gives the game its oppressive tone, where the enemy is not just numerous but fundamentally alien. The story unfolds more through implication and environment than exposition, allowing the player to piece together the scale of the catastrophe through exploration, encounters, and the slow realization that humanity is vastly outmatched by what it has unleashed. Gameplay revolves around managing a small squad of survivors tasked with venturing into hostile zones to gather supplies, uncover information, and push back against overwhelming threats. Before each mission, players must prepare carefully, selecting personnel, weapons, and limited equipment. Once deployed, the game shifts into real-time tactical control, where positioning, timing, and role specialization are critical. Soldiers serve as frontline combatants, engineers construct defensive structures such as turrets and barricades, and medics are essential for keeping the squad operational during drawn-out engagements. Losing a single member can drastically alter the balance of a mission, reinforcing the sense of vulnerability that defines the experience. One of the game’s strongest elements is how it forces players to constantly weigh risk against reward. Staying longer in a zone may yield valuable resources, but it also escalates enemy pressure, eventually triggering relentless waves that can overwhelm even well-prepared squads. Retreating early preserves lives and supplies but may slow long-term progress. There are no safe choices, only calculated ones, and this constant tension is what gives the game its identity. Ammunition, fuel, and medical supplies are always scarce, and careless spending early on can lead to catastrophic consequences later. Progression is gradual and earned through survival rather than conquest. As the campaign advances, squads can expand in size, gain access to better equipment, and develop specialized skills that improve efficiency and survivability. Early missions often feel brutal and unforgiving, but this difficulty curve is intentional, teaching players to respect enemy behavior, terrain, and the importance of preparation. Over time, mastery emerges not from overpowering foes, but from learning when to fight, when to fortify, and when to flee. Visually, Chromosome Evil embraces a retro pixel-art aesthetic that complements its bleak tone. The top-down perspective keeps encounters readable while maintaining a sense of claustrophobia, as narrow passages and limited sightlines heighten tension. Environments are sparse and decayed, reinforcing the feeling of a world consumed by something far beyond human understanding. Sound design plays an equally important role, using ambient noise and sudden audio cues to create unease and signal imminent danger without relying on overt jump scares. The game’s difficulty and systems are unapologetically demanding, which can be intimidating for newcomers. There is little hand-holding, and early failures are common as players learn the mechanics and rhythm of survival. However, this harshness is also what makes success feel meaningful. Each completed mission and each squad saved from annihilation carries a sense of genuine accomplishment that more forgiving strategy games often lack. Ultimately, Chromosome Evil is a focused and atmospheric tactical survival experience that rewards patience, planning, and respect for its hostile world. It is not designed for players seeking fast-paced action or large-scale battles, but for those who enjoy emergent strategy, oppressive horror themes, and the constant pressure of survival under impossible odds. Within its niche, it stands out as a grim, methodical journey where every victory is hard-won and every mistake is costly, leaving a lasting impression through its blend of strategy and dread. Rating: 8/10
Pensem em um joguinho tosco viciante em que você não consegue parar enquanto não chega no fim ? É esse daqui. Se você curte indie, vai sem medo. Recomendo.
Weapons free in the chemical plant results in instant game over.
小巧有趣的游戏
Good indie worth the price Got mild bugs but none of them critical
panic, right click, panic, right click, repeat
Awesome little game. It's the only thing to scratch the same itch as Strain Tactics, an incredible tactical shooter with a similar premise from five years earlier. While Strain Tactics is a more varied, polished, and overall a larger game, Chromosome Evil is a very worthy low-budget companion to it, it makes perfect sense they're bundled for sale here on Steam. I will be honest; if this game looks interesting to you, I have to recommend Strain first - it's a similar concept with a larger feature-set, including a rich morale system, more NPC activity, and more features overall. I mean no insult to Chromosome Evil, I suspect they'd agree, but you should absolutely play both games. If you're short on money, Strain will give you more for your coin - if you're just eager to play this kind of rich tactical horror and you have the patience for a series without burning out, though, get all four games and play Strain last as the finale =) In short, Chromosome Evil is a really horrible road-trip across a ruined country. Each run you attempt will begin simple, with parasitically infested zombies slowly harrassing your scavenging runs - but you'll soon unlock research and development, improve your troops' equipment while making difficult choices between approaches, priorities and investments, and end up fighting much worse things in increasingly tactically challenging and rewarding ways. Be warned, it is a real-time tactics game, and it does have an active pause system [b]but you need to progress some distance into the game and make a major investment of rare resources to unlock it[/b]. Until you do so, you'll be in a harsh realtime tactical challenge, multitasking 2-3 soldiers in combat as they try to provide mutual cover while looting, interacting with computers, repairing objectives and so on. I believe the sequel gives you the pause system from the start without restriction, so if you're easily overwhelmed by realtime multitasking, you might want to jump straight to the second game. Ultimately it's a little janky, it can seem a little simple, and it isn't entirely free of bugs - pathfinding and weapon-swapping can be really rough and require a lot of extra clicks - but I've had a really good ~11 hours with it so far and I'm not bored with it at all. I'm enjoying the slow reveal of the plot, the unique missions at milestones, and the way familiar locations can be more varied than expected when scavenging similar locations during your journey. It's worth the price and your time, please give it a try =) Oh, on that note I think CE2 has a demo which is fairly representative of how CE1 plays, just a little more advanced and smoother, so try that and see if you want to step back to the first game or jump right in to the sequel. Enjoy, and thanks for the good times, 16 BIT NIGHTS.
Охрененная зомби-стратегия. Нужно следить за ресурсами, не тратить время, патроны и тд. можно кучу всего прокачивать, и главное уметь управлять героями. Сюжет интересно узнавать по ходу игры, персонажи сами могут рассказать что-то интересное. Игра становится очень сложной на поздних стадиях из-за уровня эволюции, поэтому нужно правильно расставить приоритеты, что лучше прокачать, каких людей взять в команду и всякое такое. Более того, есть вторая часть и я определённо поиграю в неё "Они говорили что такой псих как я сдохнет первым! Впрочем... не смешно."
3/5 star
Got this game as an early Christmas gift and all I can say is that this game is brutal! Every single decision you make has a cascading effect on your playthrough and I unfortunately made poor decisions in my first playthrough that ultimately caused me to fail, Hopefully you can do better!
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Trends
Concurrent players on Steam, sampled daily since tracking started.
Audience
Estimated from the language of this game's reviews — a proxy for where players are, not official Steam demographics.
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