Two main issues.
One is information exposure and clarity. Descriptions of status effects and equipment effects are often ambiguously written or missing important information. Seeing enemies rolling dice is next to meaningless when you don't know which moves the numbers on their dice correspond to, and you're not going to memorize the numbered moveset for every enemy. Enemy passive effects are important enough that if the player knew about them in advance, they might make some strategic choices-- shuffling dice or equipment around, or choosing a different lucky number-- but by the time the player can see the passive effects, it's too late to do any of that, so the opportunity for strategic choice is lost. That would be fine if there were enough strategic choice to be made in other areas, but...
Issue two is the lack of interactivity and couterplay. With very rare exceptions, the player's gameplan and the enemy's gameplan don't really interact with each other: you may tweak your loadout before combat, but once combat starts, your loadout lets you pursue victory in a single inflexible fashion rather than anticipating or responding to individual opponents' tactics. To borrow a CCG term, rather than interacting with each other, you're playing solitaire against each other, and you win or lose based on whether your solitaire game is stronger than theirs. There's lots of status effects, lots of passive effects, and lots of little mechanical interactions between your dice and the situations in which you get to use them, but they generally don't create situations where you're playing differently because of something your opponent did, apart from binary decisions like 'I got hit, I need more shield now' or 'My battery got drained, I need more energy now'.
The poison status effect is a good example of this. Poison is threatening because it ignores your shields, inflicting health-damage directly in a game where damage the player suffers carries over between fights and healing-sources are limited. Having different kinds of threats is good if it makes you think about and play around them differently, but in this case, you generally have no means to influence whether your opponent uses poison, no means to avoid poison when it is used, no means to avoid or mitigate the damage poison inflicts once you have it, no means to actively reduce or remove the poison stacks, etc. It's a part of your opponent's gameplan that, with rare exceptions, you cannot interact with or 'play around' in any way. This no-interaction no-counterplay style pervades the whole game. If an enemy has 3 stacks of dodge, ensuring that your next 3 attacks will miss, you can't wait them out or remove them in some alternate efficient style; whether you do it now or later, you're just going to have to attack through them. If an enemy has a buff that will inflict an ailment next time you attack their shield, likewise you can't outwait or remove it; one way or another you are going to take that ailment because you are going to have to attack. So regardless of which such tactics your opponent uses, the way you approach the fight is unchanged.
This is unfortunate because the rest of the mechanical design seems fairly thoughtful. Equipment and effects are varied; changing your equipped dice makes you think about not just how big the numbers are and how reliable their distribution is but whether there's a good lucky-number distribution between all your primary dice and whether the added effects on the dice are good for the situations in which you expect to be using those dice. The charge mechanics feel novel and are sometimes interesting to play around. So, design wise, they're halfway there, but there needs to be meaningful choices to make inside of combat rather than just outside of it. Of the four or so runs I played, the strongest one involved a loadout that didn't allow me to make any combat choices at all; the character could only attack, every turn, and it did so right through the normal final boss and the one after that. it turns out taking away your ability to make choices isn't a downside when you didn't have meaningful choices to make in the first place.
There's other balance issues, such as how heavily early equipment RNG dictates whether a run is a cakewalk or an impassable slog, but that's a tertiary concern compared to the game lacking a strategic core.
