
You are a disease. Infect the human body as a lone pathogen in this cellular roguelike shooter. Collect organelles to evolve your parasite in a microscopic arms race against your host's immune system. Conquer a beautiful, procedurally generated world of tiny proportions.
Modeled estimate, not a reported figure. How we estimate →
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About
In Pathogenic, you are the disease. Experience a visceral 2D roguelike twin-stick shooter where you play as a lone parasite fighting a desperate war against the immune system. Your goal is simple: infect and conquer your human host.
To survive, you must adapt. Hunt down enemy cells, rip out their organelles, and graft them onto your own body. Evolve from a simple cell into a complex engine of destruction. Create powerful, game-breaking builds and become the ultimate pathogen.
Loot, graft, and assemble your parasite from dozens of unique organelles. Combine flagella for movement, mitochondria for power, secretors for ranged attacks, and spikes for melee combat. Chain organelle effects and discover powerful synergies to build an unstoppable disease vector.
Battle a diverse roster of enemies, from basic immune cells like macrophages and T cells to rival parasites such as tapeworms or protozoa. Formidable bosses are lurking deep within the host's organs.
Collect plasmid fragments to permanently upgrade your parasite's plasmid tree between runs. Each parasite will have it's own upgrade tree allowing for a range of builds to suit your preferred playstyle.
Navigate the procedurally generated organic landscape of the human body. Travel through distinct biomes like the branching pathways of the lungs, the pulsating chambers of the heart, and the complex neural network of the brain.
Our detailed, colorful world is powered by a soft-body physics simulation, giving every cell, enemy, and projectile a uniquely satisfying organic feel. The combination of hand-crafted design and procedural generation ensures endless variety - each run offers a fresh and challenging gameplay experience.

Genres
Stats
All-time low is the lowest price we've recorded for this game since we started tracking it.
Languages: English, Czech, Portuguese - Brazil, Simplified Chinese, French, German, Italian, Spanish - Spain, Russian, Japanese, Korean, Turkish
Engagement
Hours played at review time, across 200 reviews with recorded playtime.
Reviews
Themes across 200 recent reviews and how positive each mention is. A keyword signal, not full sentiment analysis.
positive critical· bar length = how often the theme comes up
Reviews
슈팅계열 로그라이크 예전 아이작 처음 잡았을때의 그 느낌남 스테이지별로 난이도 가파르게 올라가서 꽤 매운맛임
Vraiment superbe ! 🧬 Le jeu me fait penser à un vieux jeu sur Amstrad – Voyage Fantastique – qui était lui‑même tiré du film – Le Voyage Fantastique – où ils avaient miniaturisé un homme pour l'injecter dans le corps 🩺🦠 d'un humain pour le soigner. Il y a bien longtemps que j'attendais de voir un jeu du genre avec des graphismes de notre époque. J'avoue ne pas être déçu. Tout est super : la musique 🎶, le jeu est bien fini, il est beau. Et je n'ai pas tout vu, mais il y a l'air d'y avoir pas mal de possibilités 🧫, avec des petites vidéos d'un chercheur 🔬 dans un laboratoire entre les niveaux pour se mettre bien dans l'ambiance. De plus, il n'est vraiment pas cher et je vous le conseille fortement, 3 fois par jour, matin, midi et soir... 😄💊
挺好玩的游戏,这款肉鸽玩法特别新颖,通过细胞组合来进行升级。 游戏的细菌设定的特有创意,在玩法上也看得出制作组下了很大的功夫,但是武器随机性太高了,有时候开局遇到了不好的只能重开,到后面的关卡就是堆数值,总体来说比较符合我的预期,可以的,希望出动物身体的dlc。
This game is brutal. It is a tough as nails twin stick shooter well your build choices make a huge difference in your success. Each element is super interactive and has dramatic implications on your success. Like many space twin stick shooters it has a modular design to the creation of your ideal pathogen, you have internal and external slots what this game does which is a bit more special is that many of these components that you choose empower the connected elements around them. By combining certain infusers you can create insanely powerful combinations and apply them to weapons and skills which can potentially cause them to wildly grow in power. This is very satisfying when you pull it off successfully. There are also certain combinations which synergize incredibly well with certain pathogens. For instance, the nanobot has 1 health and gets a ton of armor as you play. There is a mutation which gives you 40% attack speed when below 2 health. This means you can keep it up with 100% uptime and you can take the ability multiple times. With some slower attacks, they become incredibly strong and fast with this combo. There are also certain modifiers you can get like cancerous which makes the organelle replicate and overwrite other similar organelles. If you have a favorite weapon that is cancerous, you can take random weapons and they will gradually mutate into the cancerous one. There are also mitochrondria, which have various conditions and then generate power for abilities or overpower infusers and abilities. By combining various elements you can make some insane builds. You can also freely bind your weapons and abilities to different buttons to have more flexibility. As you go through the game, you also get mutations which grant various bonuses and at certain intervals allow you to gain additional slots or change your slots into internal, external, overcharged, omni slots, or bonus damage slots. You also have a persistent progression mechanic where you can level up your pathogen with plasmids. Leveling them the first time with a pathogen cost extra and then raises the cap for all pathogens. With the higher cap, if you have another pathogen you want to level, its much cheaper to level up so once you reach various caps you can really try a lot of different things. My favorite is probably the co op setup. It plays a bit like twin cop or something, you each control half of a pathogen. You can build them out independently and each player controls them on their own. It is actually pretty overpowered in the slots its given but by splitting the workload, it can become very cumbersome as you have to synch up and work together when it comes to dodging in a bullet hell. Its very satisfying. The game also has a difficulty modifier thing once you beat it and it allows you to customize your gameplay bigtime for big rewards, this heavily reduces the grind. Overall, its a great roguelite, especially for its price. One of my favorite things in most games is when they have a local co op mode
'내가 질병이 된다'는 발상 하나만으로도 신선했던 로그라이크. 소기관을 조합해 점점 강해지는 빌드 만드는 재미가 뛰어나고, 한 판 한 판이 달라서 계속 "한 번만 더"를 외치게 됩니다. 다만 운이 안 좋으면 면역세포에게 백신 맞은 것처럼 순식간에 녹아내릴 수도 있습니다. 로그라이크와 빌드 조합을 좋아한다면 강력 추천! 단, 이 게임을 하고 나면 몸속 면역세포들에게 괜히 미안해질지도 모릅니다.
I played this game extensively during the demo and i t was a blast then. Also the full install pulls over your progress from the demo. The graphics are just gorgeous. The upgrade system is easy to use yet complex and deep allowing for all manners of play and strategy. The enemies are all unique and unique attacks and purposes. Did I mention the visuals? The speed of the game is superb. The soundtrack is so relaxing. You can't beat the launch price for such a fun game.
Solid game, clean controls and a very reasonable price.
너무 재밌습니다 여러가지 무기를 조합하고 나만의 질병?? 을 만들어서 인간 병원체를 죽여보아요~
별기대 안하고 샀는데 더 해봐야겠지만 생각보다 재밌음. 맵 클릭으로 원하는 곳에 이동할 수 있어서 속도감도 좋고 뭐든 여기 붙였다 저기 붙였다 해서 조합이 생각보다 다양한 느낌.
Hades, только ты глист. 10/10
Related
Related
Trends
Steam followers (game-group members) tracked daily from when we started recording.
Momentum
Pace estimated from the game's recent review growth (our daily snapshots) at its own sales-per-review ratio — a momentum signal, not booked sales.
Audience
Estimated from the language of this game's reviews — a proxy for where players are, not official Steam demographics.
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