
COMBINE WEAPONS in the microscopic roguelite turret shooter with macroscopic depth. Survive 6 modes using an astounding array of turrets, perks, mutations and power-ups on this psychedelic journey to the heart of the abyss. Shmup Mode turns it into a vertical shoot 'em up!
Modeled estimate, not a reported figure. How we estimate →
Discounts
Every price cut of more than 20% we have observed, in each market that quoted one, with this game's chart position on either side of it. These are episodes, not a model: a sale is one event, and one event cannot tell you what the next one will do.
Reviews, worldwide (the counter carries no country): 0/day in the week to Aug 28 → 0.14/day in the week after.
Reviews, worldwide (the counter carries no country): 19/day in the week to Jul 16 → 0.14/day in the week after.
For scale, across Steam · Top Sellers · Brazil over the last 30 days: the 26 chart moves that followed a price cut of more than 20% went a median of 7 places towards #1, and the 2,400 moves with no price cut behind them went 2 away. One store, one chart, one country — it is the only place we have enough observations to say even that.
Prices outside the United States have been collected since 6 August 2026 and chart positions since 19 July 2026, so a cut older than that has no market to compare and a market that joined later has no history yet. Nothing here is converted between currencies.
About
Dive into the microscopic world, radiating with bioluminescent life and unspeakable horrors. Genome Guardian is a deeply-complex shooter that's easy to pick up but hard to master. Research permanent upgrades to survive a variety of microbes across 6 game modes, each with multiple "depths".
Pair DNA nucleotides Adenine (rapidfire), Cytosine (precision), Guanine (spread), Thymine (explosive) to discover wild hybrid bioweapons!
Bomb + Shotgun combines explosives with spread to create Blast Shotgun!
Bomb + Bomb doubles down on explosive power to make Bazooka!
Blast Shotgun + Shotgun forms the all-powerful Flak Cannon!

49 Turrets with unique strengths and functions
96 Perks to mix and match that drastically change how you play
75 Weapon & Turret Mods that can turn shots into sticky laser mines or bouncing fireballs
64 Mutations alter the challenges you face each run

20-minute Runs that can be continued in Endless Mode
75 Bassy Electronic Tunes that adapt to the current mood & intensity
Cosmetics like spider legs and tank tread
Accessibility Settings for colourblindness, motion sickness, and even arachnophobia!
100 Steam Achievements
Steam Trading Cards
Cloud Save
Plays great on Steam Deck!!!

Engagement
Reviews
Themes across 45 recent reviews and how positive each mention is. A keyword signal, not full sentiment analysis.
Reviews
The demo covers pretty much every interesting part of the game. Serviceable for a few hours, but annoying and too repetitive after that. The developer's stance on some of the game's issues is disappointing. Wouldn't recommend buying.
If you need a game you can return to when you need a quick 15-30 mins to fill, genome guardian has your back. Wonderfull bitesized turret defense game that has tons of replayability and fits the "easy to learn, hard to master" umbrella perfectly. Also: Little lore mystery thats uncovered gradualy by progressing through the difficulties relates back to the game structure itself, Chef´s kiss. On a note unrelated to the game: Dev really stepped up when i had a savefile issue, having me up and running within minutes. Thank you so much again, and all the best for GG2! Can´t wait.
Media

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Price dynamics, follower growth, revenue and sales trajectories with interactive tooltips
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Genres
Stats
All-time low is the lowest price we've recorded for this game since we started tracking it.
Languages: English
Hours played at review time, across 46 reviews with recorded playtime.
positive critical· bar length = how often the theme comes up
Glitch that ruined my run in second to last wave aside, it's been just meh. wouldn't've bought the game if I didn't like the idea of unlocking all the different weapon combinations and filling out the meta progression, but it turned out disappointingly dull. I did like trying the combinations and filling out the weapon arsenal at first, but even that gets old real fast tbh, the meta progression is easily maxed out in a couple of hours and all that's left are the same monotonous runs, there are barely any roguelike factors that can make your run schizo fun. Even when you demolish everything on your screen, the amount of waves you have to sit through for some of the achievements is way too high and takes long while being unfun even if you want something to afk in while enjoying podcasts/music.
good game
A tower defence game where you only have one tower. Works surprisingly well.
this game is so dang fun when it comes to all the weapon customizations, i havent even gotten halfway and i unlocked the jocker tower and it sped run me through the game and i ended with like 3k moneys and honestly was astounded by the randomized gameplay, this is one of the most replayable games ive ever seen with a few thousand hours of gaming
I'm not fully done with this game but I've loved how the game works and how creative you can get with these builds.
Fun Fun Fun
its godd, i guess
Players by region
Where this game's players are, estimated from review languages.
Related
| Game | Estimated lifetime revenue | Reviews | Review score | Price |
|---|---|---|---|---|
| $1.2K | 15 | 100% | $3.50 | |
| — | 0 | — | — | |
| $570 | 3 | 67% | $7.99 | |
| $56 | 3 | 67% | $0.99 | |
| — | 0 | — | — | |
| — | 0 | — | — |
Related
| Game | Estimated lifetime revenue | Reviews | Review score | Price |
|---|---|---|---|---|
| $240.3K | 1.5K | 64% | $4.99 | |
| $240.4K | 450 | 61% | $14.99 | |
| $240.2K | 420 | 84% | $8.95 | |
| $240.1K | 1.7K | 85% | $12.99 | |
| $240.1K | 363 | 59% | $19.99 | |
| $240.6K | 630 | 85% | $8.39 |